Pretty much always. Pitchers working up in the zone throw 4 seam and when needing a strike over the plate (hate that one). Typically, when they working the lower half of the zone they throw a 2 seamer. The pitcher/catcher can change this up as they see fit if something isn't working that day.
I wish I could say this gameplan always works as planned but when dealing with HS pitchers things can get a little convoluted.
The HS coach lets the catcher call the game usually once he proves decent at it. Both Freshman and JV teams let the catchers call pitches so they get ready for Varsity. If the coaches don't like what they see, a quick meeting in the dugout happens when the catcher/pitcher come off the field.