Not directly familiar with these leagues but took a quick look. Options are often limited for JC freshmen and these two leagues look typical for those players. Both leagues seem to have decent structure behind them. Both seem to be heavy on players from their immediate region so that may be something to consider, depending on where your son lives and goes to school. The Midwest seems to have guidelines more stringent to true summer college baseball where all players are college players while it looks like the other allows for a bit of outliers. Also, there are a few specific teams with red flags... older (men's league age) players mixed in, record of 3-38, etc.
As was discussed in a recent thread, some important questions to ask are how playing time will be allocated, what living arrangements are and what total expenses are likely to be.