Just sticking my head out of the foxhole for a moment - but verlander just threw 2 cbs right down the middle to ARod who didn't even twitch. Now, verlander may have missed his spot or maybe not. I think that there are general rules (e.g., don't groove a ball down the middle); exceptions to the general rule (e.g., throw a ball down the middle if you can fool the batter; or if you want to get an out on a sacrifice); exceptions to the exceptions, etc.
I think it shows that baseball is a thinking man's game; a game of constant adjustments; a game that is much "faster" then the non-baseball fan could ever imagine. A game which presents lots of cliches (e.g., he really grooved that pitch) for every occasion (e.g., he blew that high cheese right past him) all of which prove any point a fan wants to make.
I think the bottom line for a pitcher is throw whatever and wherever you need to get the batter out.