Moneyball isn't about tactical baseball strategy, it's about understanding the relative value of particular baseball skills at a strategic level in the marketplace of professional baseball. It's got far more in common with quants and Wall Street than it really does with tactical baseball decisions.
HS baseball doesn't have remotely the sort of free market for talent/skills that pro ball does, so identifying undervalued skills in your player pool, to the extent that you could do so with easily available information, has much less value. I mean, you can't just freely swap skill sets by trading guys or signing a FA, for instance.
That said, there are no doubt strategies that are poorly matched to player skill sets by coaches at the HS level (or any other level, I suppose) all the time, and you could apply some sabermetric ideas/processes towards identifying what does/doesn't work for the players/environment you do have to work with. It's going to be hard to do it systematically/scientifically given the general time/data constraints a typical HS program faces combined with the "old school" mentality that might be more prevalent at lower levels where profit motive doesn't ultimately come into play to winnow out sub-optimal strategies faster.
But in the end, what wins ball games at any level is the same, score more runs than the other guy. And it should be possible to quantify and improve the skills that lead to that in useful ways if you got the time/motivation to do so.