Target

Professionally, you set up a target at the last second, but some of my pitchers want it up the whole time. I do what my pitcher prefers.

StyleMismatch,
The target is still given it is just not given as early or as pronounced as it is in youth ball or high school. This eliminates the hitter or another member of the offense from knowing the location of the pitch. Understand that most catchers’ signs indicate to the pitcher where the pitch will be thrown so the pitcher knows if the catcher will ultimately set up inside or out. What I've heard and read is that when you focus on an object like the catcher’s mitt, that focus is more “focused” in the first few seconds and diminishes very rapidly after those first few seconds.
Fungo

I typically signal the location immediately after I give the pitch signal. Whether it is with the same hand or with the glove hand it just depends.

Also, along the same lines, how do you guys give your target? With your hand I mean..
My coach teaches us to have a more relaxed target showing the top of the glove rather than the entire pocket. This allows the wrist to relax some and not be as stiff.

I have heard people say to open your glove, almost like a pancake, then have your wrist, so the glove is perpendicular to the ground, so the pitcher has a bigger target. I don't lie that, makes my wrist tense, but I think as long as you have your glove there, there is a arget for them to throw to.

As an addendum to Fungo's post, keep in mind that the target isn't always the glove --- it could be a rivet on the shin guards, a spot on the mask, a point on the shoulder of the catcher --- depends on the pitcher, the pitch, and the battery's communication.

The pitcher isn't the only guy who can tip pitches; the catcher can as well by setting up too early.

I never thought of that, I need to tell my pitchers to focus on a part of my body or gear to throw at, i know a lot of time I am able to get a headstart on the pitcher because I glance back at the catcher who's got his glove way far out where I can easily see it, so I know before the pitch is even thrown, where I want to hit the ball. Yeah, it's cheap, but it's like figuring out the 3 base coaches signals.